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Lilly commits approximately 20% of total sales to its R&D program, focused on developing novel therapies in four core areas, neuroscience, endocrine disorders, cancer, Cialis commercial and cardiovascular diseases. Commercial launches began in Europe, New Zealand and Australia in February, and culminated in the United States and cialis commercial canada in November. The decrease was due to the discontinuation of activities associated with the Pafase and endothelin receptor antagonist programs, partially offset by increased costs related to the progression of development activities for our clinical product candidates.
Fitch's concerns include the company's modest free cash flow generation since 2002, negatively affected by large dividends and heavy investment in capital. Elsewhere, Lilly has rights to cialis commercial market Cialis, and pays a royalty, to Lilly ICOS, equal to 20% of net product sales in those territories. Fitch cialis commercial will continue to monitor the appeals process and the progression of patent challenges to Evista.
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